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Pollock AJ, Zaver SA, Woodward JJ A STING-based biosensor affords broad cyclic dinucleotide detection within single living eukaryotic cells. Nat Commun. 2020; 11: 3533.

Luteijn RD, Zaver SA, Gowen BG, Wyman SK, Garelis NE, Onia L, McWhirter SM, Katibah GE, Corn JE, Woodward JJ, Raulet DH. SLC19A1 transports immunoreactive cyclic dinucleotides. Nature. 2019 Sep;573(7774):434-438.


An J, Woodward JJ, Lai W, Minie M, Sun X, Tanaka L, Snyder JM, Sasaki T, Elkon KB. Inhibition of Cyclic GMP-AMP Synthase Using a Novel Antimalarial Drug Derivative in Trex1-Deficient Mice. Arthritis Rheumatol. 2018 Nov;70(11):1807-1819

McFarland AP, Burke TP, Carletti AA, Glover RC, Tabakh H, Welch MD, Woodward JJ. RECON-Dependent Inflammation in Hepatocytes Enhances Listeria monocytogenes Cell-to-Cell Spread. mBio. 2018 Jul 5;9(3):e00526-18.

McFarland, A.P., Luo, S., Ahmed-Qadri, F., Zuck, M., Thayer, E.F., Goo, Y.A., Hybiske, K., Tong, L. and Woodward, J.J. Sensing of bacterial cyclic dinucleotides by the oxidoreductase RECON promotes NF-κB activation and shapes a proinflammatory antibacterial state. Immunity. 2017; 46(3):433-445.

McFarland, AP, Woodward, JJ Flying Under the Radar: Immune Evasion by Group B Streptococcus. Cell Host and Microbe. 2016, 20 (1): 4-6.


Huynh, T.N., Choi, P., Sureka, K., Ledvina, H.E., Campillo, J., Tong, L.*, Woodward, J.J.* Cyclic di-AMP targets the cystathionine beta-synthase domain of the osmolyte transporter OpuC. Mol Microbiol. 2016 Jul 5.


Huynh TN, Woodward JJ. Too Much of a Good Thing: Regulated depletion of c-di-AMP in the bacterial cytoplasm. Current Opinion in Microbiology. April 2016: Vol. 30, 22-29.

An J, Woodward JJ, Sasaki T, Minie, M., Elkon, K.B. J. Cutting Edge: Antimalarial drugs inhibit IFN-β production through blockade of cyclic GMP-AMP synthase-DNA interaction. J Immunol. 2015 May 1;194(9):4089-93


Huynh, T.N., Luo, S., Pensinger, D., Sauer, J.D., Tong, L.*, Woodward, J.J.* An HD-domain phosphodiesterase mediates cooperative hydrolysis of c-di-AMP to affect bacterial growth and virulence. Proc. Natl. Acad. Sci. USA. 2014.


Sureka, K., Choi, P.H., Precit, M., Delince, M., Pensinger, D., Huynh, T.N., Jurado, A.R., Goo, Y.A., Sadilek, M., Iavarone A.T., Sauer, J.D., Tong, L.*, Woodward, J.J.* The cyclic dinucleotide c-di-AMP is an allosteric regulator of metabolic enzyme function. Cell (2014). Volume 158, Issue 6, p1389–1401, 11 September 2014

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